The total cholestasis treatment market will expand due to the rising prevalence of obstetric cholestasis.

  The liver is involved in the regulation of several facets of lipid metabolism. The liver primarily produces bile, which contains components that are required for fat absorption in the gut. Furthermore, biliary discharge of cholesterol and phospholipids into the gut plays an important role in maintaining body lipid homeostasis. In addition to supplying plasma lipoproteins, the liver also manufactures apoproteins, which are responsible for regulating several metabolic interconversions across lipoprotein classes. It also controls the lipid components of lipoproteins, such as triglycerides, cholesterol, and phospholipids.


Cholestasis is a condition in which the liver's bile juice is unable to pass to the duodenum. Cholestasis can be classified into two types: obstructive cholestasis and metabolic cholestasis. There is a clog in the duct system that transports bile from the liver in obstructive cholestasis, whereas in metabolic cholestasis, there is a problem with bile synthesis in the liver. The former can be caused by gallstones or cancer, whilst the latter can be caused by genetics or drug adverse effects. Itching, jaundice, pale stool, and dark urine are all signs of cholestasis.


Obstetric cholestasis is one of the most common kinds of cholestasis. Obstetric cholestasis affects 0.7 percent of pregnancies in multiethnic societies, as well as 1.2–1.5 percent of pregnant women of Indian or Pakistani descent in England, according to the Royal College of Obstetricians and Gynecologists. Both hereditary and environmental variables influence the frequency of obstetric cholestasis. The data varies by population around the world. In Chile, for example, 2.4 percent of all pregnancies are affected. The global prevalence of this disease is increasing, which will drive the entire cholestasis therapy market forward.

Growing prevalence of obstetric cholestasis to drive growth of the overall cholestasis treatment market

Intrahepatic cholestasis of pregnancy (ICP) or obstetric cholestasis, according to a report published in the National Center for Biotechnology Information, is the most common liver illness during pregnancy. Obstetric cholestasis is a reversible condition that usually develops in the second or third trimester of pregnancy. Pruritus (severe itching of the skin), particularly in the palms and soles, is present, as are elevated serum aminotransferases and bile acid levels. The prevalence of cholestasis is predicted to rise in the near future as the number of pregnancies rises. Furthermore, cholestasis can be inherited.Because of the nature of the disease, persistent cholestasis affects a large number of youngsters. Hereditary biliary atresia and intrahepatic cholestasis are the leading causes of chronic liver disease in children, according to the National Center for Biotechnology Information. They also serve as critical indicators for liver transplantation in children. Children are more likely to contract the disease as the population grows. During the projection period, this will propel the entire cholestasis treatment market forward.

Eli Lilly and Company, Palmetto Health, Asklepion Pharmaceuticals, LLC, and Abbott Laboratories are some of the leading players in the cholestasis treatment market

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